大腸鏡檢查前僅一日低渣飲食會影響腸道清潔程度嗎?Does one day low-residue diet before colonoscopy affect the cleanliness of intestines?

328 1 90

2024-02-19 已刊登
新刊登 綜 整 預防/治療/介入類型

作  者

謝磁芬 林欣儀 李佩芯 江承晏 蔡美菊*

文章類別

B 類:實證健康照護應用

問題類型

治療/預防性問題

健康狀況

胃腸肝臟系統 (Gastroenterology and Hepatology)  

治療/介入措施

生物行為相關措施(Bio-behavioral Intervention) - 一日低渣飲食控制

專長類別

消化、內分泌

中文關鍵詞

#大腸鏡檢查 #低渣飲食 #腸道清潔程度

英文關鍵詞

#Colonoscopy # low residue diet # bowel cleanliness

機構名稱

長庚醫療財團法人桃園長庚紀念醫院

申請單位

健康檢查中心

中文摘要

形成臨床提問:
台灣罹癌人數以大腸癌的罹患人數最多,若糞便潛血檢查呈陽性時,應進一步接受大腸鏡檢查。腸道清潔度程度直接影響大腸鏡的檢查品質,要達到良好的腸道清潔程度需檢查者服用清腸藥物及配合低渣飲食控制。許多檢查者無法忍受較長久飢餓感,而對大腸鏡檢查前的準備產生不滿及排斥,因此針對檢查者需求,藉由實證護理的步驟來了解大腸鏡檢查前僅一日低渣飲食是否影響腸道清潔程度。
文獻搜尋的方法與分析:
針對此提出臨床問題,並設定PICO,以布林邏輯「OR」、「AND」串聯P、I、C、O的關鍵字,搜尋五個資料庫,且運用「limit」設限搜尋隨機對照試驗及系統性文獻。搜尋到98篇文獻,藉由閱讀主題和摘要,排除重複、不符合主題或其他介入措施之文獻共95篇,最後以3篇證據等級較高隨機對照試驗文獻進行評讀。
文獻的品質評讀與結果:
文獻評讀工具採用Critical Appraisal Skills Programme,CAPS 2020版之隨機對照試驗檢核表作為文章評讀工具,並進行效度、重要性及臨床可應用性三面向的評讀。以英國牛津大學實證醫學中心Oxford CEBM實證等級(2011)來評價文獻等級,為Level 2(治療型)。第一篇文獻研究對象為18歲以上大腸鏡檢查患者,介入措施為1天低渣飲食,對照組則採用2天低渣飲食,以BBPS量表來測量腸道清潔程度,結果2組間差異無統計學意義,次要結果顯示:1天的低渣飲食更容易被患者接受。第2篇及第3篇:文獻收納18歲以上門診結腸鏡檢查者,比較與1天低渣飲食方案相比,3天低渣飲食是否改善了腸道清潔品質。研究使用類別變數的卡方統計和連續變數的t測試進行比較,結論:證實了3天的低渣飲食準備與1天低渣飲食準備在統計學上沒有差異。
證據之臨床應用:
依據文獻結果進行實證知識轉譯,採方便取樣納入50歲~80歲26位無痛大腸鏡檢查者,將對象分為1天低渣飲食組(low residue diet, LRD)11人及2天LRD 15人,其餘大腸鏡檢查準備項目不變,兩組均採分段式服用清腸藥水,於上午執行大腸鏡檢查,由醫師於報告中呈現檢查結果及腸道清潔分級(依Aronchick scale分級),以比較兩組腸清潔程度差異及對檢查前低渣飲食控制之滿意度。
成效評值:
2022年11月26日至12月4日比較二組大腸鏡檢查者腸清潔效果佳(excellent+good)之人數比率:1天LRD組為90.9%和2天LRD組為86.7%,未達統計上顯著差異(p = .77),二組亦無不良事件產生。而二組對檢查前低渣飲食控制之滿意度:1天LRD組平均為4.91分,2天LRD組平均為4.27分,達統計上差異(p < .01),顯示介入措施能提升檢查者對檢查前準備滿意度。
結論與建議:
臨床實證應用證實能在不影響腸道清潔度的情形下,縮短飲食控制天數為1天,以減少檢查者飲食控制之不適感,增加大腸鏡檢查前準備的滿意度,此結果冀望提供其他單位臨床醫護人員健康檢查照護過程的參考依據。

英文摘要

Ask an answerable question (PICO):
Colorectal cancer has the highest incidence among all cancer types in Taiwan. If the fecal occult blood test is positive, further colonoscopy is recommended. The level of bowel cleansing directly affects the quality of colonoscopy examination. To achieve good bowel cleansing, the examinee needs to take bowel preparation drugs and follow a low-residue diet. However, many examinees cannot tolerate prolonged hunger and are dissatisfied and resistant to the preparation before colonoscopy. Therefore, in response to the needs of examinees, empirical nursing steps are taken to investigate whether a low-residue diet only one day before colonoscopy affects the level of bowel cleansing.
The Method and Analysis of Literature Review:
In response to this, a clinical question was formulated and PICO was established. Boolean logic was used to combine the keywords of P, I, C, and O with "OR" and "AND" to search five databases. The search was limited to randomized controlled trials and systematic reviews. A total of 98 articles were identified, and after screening the titles and abstracts, 95 articles were excluded due to duplication, lack of relevance to the topic, or other interventions. Finally, 3 high-quality randomized controlled trials with strong evidence were selected for critical appraisal.
Critical Appraisal:
The Critical Appraisal Skills Programme (CAPS) 2020 version of the Randomized Controlled Trials (RCT) checklist was used as the article appraisal tool, and validity, importance, and clinical applicability were evaluated. The Oxford Centre for Evidence-Based Medicine (CEBM) levels of evidence (2011) were used to evaluate the level of evidence, which was determined to be Level 2 therapy. The first article studied patients aged 18 years and older who underwent colonoscopy, and the intervention was a low-residue diet for one day, while the control group received a low-residue diet for two days. The Boston Bowel Preparation Scale (BBPS) was used to measure the level of bowel cleanliness, and the results showed no statistically significant difference between the two groups. The secondary outcome indicated that the one-day low-residue diet was more readily accepted by the patients. The second and third article studied outpatients aged 18 years and older undergoing colonoscopy to compare whether a three-day low-residue diet improved bowel cleansing quality compared to a one-day low-residue diet. The study used chi-square statistics for categorical variables and t-tests for continuous variables to compare the two groups. The conclusion was that the three-day low-residue diet preparation was not statistically different from the one-day low-residue diet preparation.
Clinical Application of Evidence:
Based on the results of the literature, we examine the effect of a 1-day low residue diet (LRD) versus a 2-day LRD on bowel preparation and patient satisfaction among 26 individuals aged 50 to 80 years who undergo painless colonoscopy. Participants will be conveniently sampled and randomized to either the 1-day(11 subjects) or 2-day(15 subjects) LRD group. All participants will receive the same bowel preparation, which will be taken in segments, and colonoscopy will be performed in the morning. The colonoscopy results and bowel cleanliness will be graded using the Aronchick scale and reported by the physician. The evaluation will compare the difference in bowel cleanliness between the two groups and the satisfaction level with the low residue diet before colonoscopy.
Evaluation of Effectiveness:
From November 26th to December 4th, 2022, the study compared the ratio of individuals with excellent or good colon cleansing efficacy between two groups: the one-day low-residue diet (LRD) group with a rate of 90.9% and the two-day LRD group with a rate of 86.7%. Neither did it reach the statistical significance(p= 0.77), nor it proceed adverse event. The study also compared the satisfaction levels of the two groups with regards to low-fiber diet control before the colonoscopy, with an average score of 4.91 for the one-day LRD group and 4.27 for the two-day LRD group. It reached the statistical difference(P<0.01), and demonstrate that the intervention enhances the satisfaction of the subjects at preparation phase.
Conclusions and Recommendations:
Clinical evidence has confirmed that shortening the low-fiber diet control period to one day is feasible without compromising the quality of colon cleansing. This approach can effectively reduce discomfort associated with diet control and improve patient satisfaction with the preparation process before colonoscopy. These results may provide a useful reference for healthcare providers in other clinical settings when managing health checkups.