Ask an answerable question (PICO)：
Build up a clinical question: explore whether doing exercise is able to alleviate the pain that osteoarthritis patients suffered with. PICO: P: 62 years old, female, diagnosed with knee osteoarthritis; I: does exercise; C: no exercise; O: pain score.
The Method and Analysis of Literature Review：
(1) The literature searching database includes Cochrane, Pubmen, Embase and the Airiti Library.
(2) Keywords are included as follows: P (Osteoarthritis, Knee, Arthritis, Degenerative), I (Exercise, sport, physical , physical exercise, recitation), O (Pain Management, Improve * of pain); keywords and PICO which is corresponded with ordering PICO of “I&POC”; Combine text term with searching with Boolean characters "OR, AND, NOT & Truncation＊”; the languages selected are Chinese and English.
(1) Qualified critical appraisal of literature: for searching results: there are total 127 articles found in Chinese and English literature databases; by deducting and removing the literature with issue of duplicate, non-RCT study, non-SR research, measures of study design do not correspond with PICO, lower grade, a total of 2 articles of literature are being appraised, with the appraising tool of CASP in the version of 2013.
Clinical Application of Evidence：
Evidence of clinical application: make the improvement by applying the 7 steps of empirical knowledge translation and make the result analysis with promoting at the same. The study design was conducted as a RCT (randomized controlled experimental) study. Study period was started from August 15th to October 20th in2019; performed in the clinic of teaching hospital of Region in Southern Taiwan. During the intervention period, the most common intervention is doing exercise (walking and muscular exercise.
Evaluation of Effectiveness：
Evaluation: with the use of statistical analysis, compare the effectiveness of pain alleviated changes before and after doing exercise in osteoarthritis patients. After the intervention implemented from August 15th to October 20th in 2019, by statistically verified the 30 cases of new patients received, the result is indicated as (1) basic information: 40% of participants are aged from 64-70 and 26.7% are aged from 51-60; gender: 52.3% of participants are women, and 46.7% are men; 93.3% of participants do not have a habit of exercise and 56.7% participants are overweight indicated by the BMI; (2) with statistical examination, there is no difference observed with pain scores of P value (>0.05) before and after the interventions of walking and muscular exercise implemented; (3) the implementation of interventions, through the summarized examining study result, it indicates that doing exercise such as interventions of walking or muscular exercise is obviously decreasing pains suffered and improve living quality, especially for the patients with osteoarthritis. However, both of intervention measures of walking and muscular exercise make no difference, no significant variance on both pain relief and living quality.
Conclusions and Recommendations：
This article is aimed to find out whether doing exercise is possible to alleviate pain that osteoarthritis patients suffered with? Through the evidenced questioning and clinical application, first building up the PICO model and then searching and screening documents related by using the strategy of evidence-based medicine; afterward critical appraised and analysis the two documents to realize that doing exercise is definitely able to ease pains suffered in osteoarthritis patients and further to improve the stiffness with joints as well as the living quality; when administering this idea to the clinical application, even the number of participant is 30 patients only, we did find out that the pain scores the osteoarthritis patients suffered with is actually eased by doing exercise after the empirical applications and further to improve their living quality, without any cost and no side effects aroused. The result is the same as the Fransen (2015) and Siew (2019). It is expected to contribute some efforts in the quality of nursing care with osteoarthritis patients.