乳癌化療病人使用耳穴按壓是否可緩解噁心嘔吐?Does Acupressure Relieve Nausea and Vomiting in Breast Cancer Patients Undergoing Chemotherapy?

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2025-03-06 已刊登
新刊登 綜 整 預防/治療/介入類型

作  者

林安信* 謝春金

文章類別

A 類:實證健康照護綜整

問題類型

治療/預防性問題

健康狀況

腫瘤醫學 (Oncology)  

治療/介入措施

臨床護理技術相關措施(Clinical Nursing Skills and Techniques) -

專長類別

腫瘤及安寧/緩和

中文關鍵詞

#乳癌病人 #耳穴按壓 #化療引起的噁心嘔吐

英文關鍵詞

#Breast cancer patients #ear acupressure #Chemotherapy-induced nausea and vomiting

機構名稱

長庚醫療財團法人基隆長庚紀念醫院暨情人湖院區

申請單位

內科

中文摘要

形成臨床提問:
化療引起的噁心嘔吐,是乳癌病人化療期間最常見的副作用,嚴重且頻繁的嘔吐會引病人的食慾不振,導致其營養缺乏、免疫力下降,影響著病人的生活品質和化療效果,止吐藥物是目前常見緩解策略,但仍高達40%病人使用後未能緩解噁心嘔吐的情形。耳穴按壓是中醫傳統的方法,可調節內分泌功能與刺激迷走神經減緩噁心嘔吐的腸胃症狀,中醫基礎國人接受度高,護理人員也可以獨立操作,但是發現沒有足夠的證據或文獻,可以衛教病人或作為照顧常規依據。
文獻搜尋的方法與分析:
本文確立臨床問題,根據 PICO 的關鍵字、同義字,以布林邏輯「OR」、「AND」串聯關鍵字及同義字搜尋,包括 The Cochrane Library、PubMed、Embase 資料庫,不設限年份與語言,得到英文文獻共16篇,以人工方式進行閱讀主題和摘要,將涉及化療中乳癌病人、耳穴按摩的文章納入,最後以PICO最符合本主題最後以證據等級選定2篇,一篇隨機對照試驗(2022)與一篇系統性文獻回顧(2021)進行評讀。
文獻的品質評讀:
此文為乳癌化療病人運用耳穴按摩緩解噁心嘔吐情形的成效,針對【Efficacy of Auricular Acupressure in Prevention and Treatment of Chemotherapy-Induced Nausea and Vomiting in Patients with Cancer: A Systematic Review and Meta-Analysis】,使用(Critical Appraisal Skill Program, CASP)工具進行評讀總分10分,其Oxford CEBM證據等級判讀結果為 Level I等級。另外針對【Effects of auricular acupressure on chemotherapy-induced nausea and vomiting in breast cancer patient : a preliminary randomized controlled trial】此文章為隨機對照試驗(RCT)使用(Critical Appraisal Skill Program, CASP)工具進行評讀總分為10分,實驗研究中的是否盲化的項目,由於有無耳穴按摩是一項顯而易見的介入措施,無法做到雙盲的研究設計因此其Oxford CEBM證據等級評定 Level II。
結果、結論與建議:
經本篇納入評讀的高品質證據,研究證明耳穴按壓對化療導 致的噁心嘔吐具有顯著的止吐作用,可作為緩解化療導致的 噁心嘔吐輔助方法,建議臨床工作人員進行培訓後,透過多 媒體衛教或團體衛教示教,推廣於乳癌病人,來改善病人化 療後的整體生活品質。

英文摘要

Ask an answerable question (PICO):
Chemotherapy-induced nausea and vomiting(CINV) are the most common side effects during chemotherapy in breast cancer patients. Severe and frequent vomiting can lead to loss of appetite, resulting in nutritional deficiencies and decreased immunity, the patient's quality of life and the effectiveness of chemotherapy. Antiemetic drugs are currently a common mitigation strategy, up to 40% of patients still experience unrelieved nausea and vomiting after their use. Auricular acupressure is a traditional Chinese medicine technique that can regulate endocrine functions and stimulate the vagus nerve to alleviate gastrointestinal symptoms of nausea and vomiting. Traditional Chinese medicine is widely accepted among the population, and nursing staff can perform it independently. However, there is a lack of sufficient evidence or literature to educate patients or serve as a basis for routine care.
The Method and Analysis of Literature Review:
This article identifies a clinical issue and searches for relevant studies using keywords and synonyms based on the PICO framework, using the Boolean operators "OR" and "AND". The search includes The Cochrane Library, PubMed, and Embase databases without restrictions on year or language. A total of 16 English-language articles were recovered. , and each article's title and abstract were manually reviewed. Articles involving chemotherapy in breast cancer patients and auricular acupressure were included. Ultimately, based on the best fit with the PICO framework and evidence level, two articles were selected for a detailed review: one randomized controlled trial (2022) and one systematic review (2021).
Critical Appraisal:
This article discusses the effectiveness of auricular acupressure in alleviating nausea and vomiting in breast cancer patients undergoing chemotherapy Critical review of the article "Efficacy of Auricular Acupressure in Prevention and Treatment of Chemotherapy-Induced Nausea and Vomiting in Patients with Cancer: A Systematic Review and Meta-Analysis" using the Critical Appraisal Skill Program (CASP) tool, which scores it 10 out of 10. The Oxford Center for Evidence-Based Medicine (CEBM) levels of evidence rates it as Level 1. Additionally, the article "Effects of auricular acupressure on chemotherapy-induced nausea and vomiting in breast cancer patients: a preliminary randomized controlled trial" is a randomized controlled trial (RCT) also reviewed using the CASP tool, scoring 10 out of 10. Due to the visible nature of the auricular acupressure intervention, it is not possible to implement a double-blind study design; therefore, its Oxford CEBM evidence level is rated Level 2.
Results, Conclusions and Recommendations:
Based on the high-quality evidence included in this review, studies have proven that auricular acupressure has a significant antiemetic effect on chemotherapy-induced nausea and vomiting. It can be used as an adjunctive method to alleviate chemotherapy-induced nausea and vomiting. It is recommended that clinical personnel receive training and use multimedia health education or group teaching demonstrations to promote this method among breast cancer patients, with the aim of improving their overall quality of life after chemotherapy.