Ask an answerable question (PICO)：
Post-dural puncture headache (PDPH), a common complication of dural puncture (DP). In the clinic, bed rest of 6 hours at least is a commonly used method to prevent PDPH. However, the headache may still be present even after bed rest. Accordingly, the objective of this article was to explore whether bed rest can or cannot prevent PDPH.
The Method and Analysis of Literature Review：
This study established keywords and were combined synonyms with PICO and Medical Subject Headings term, with Boolean logic principles to systematically search for the research evidence. We searched the Cochrane Library, Embase, PubMed, and Airiti Library (Chinese Electronic Periodical Service) for systematic review and meta-analysis investigating the effects of bed rest in preventing PDPH before January 2021. No language restriction. A total of 10 articles were retrieved. After deleting the duplicated, the title and abstracts of the remaining study were reviewed based on the inclusion and exclusion criteria. Finally, there was 1 systematic review and meta-analysis article included in this study.
Critical Appraisal：
This systematic review and meta-analysis article included was identified as Level 1 according to the 2011 Oxford Centre for Evidence-Base Medicine Levels of Evidence. The evaluation validity, importance, and practicability of the 2018 Critical Appraisal Skills Programme Systematic Review Checklist. According to literature review, there was no significant difference between bed rest and immediate mobilization for preventing PDPH in patients with DP.
Results, Conclusions and Recommendations：
In sum, bed rest does not prevent the PDPH. We suggest that bed rest should not be routinely recommended to patients after PD. We even support that early mobilization after PD decrease the cost of nursing caregiving. However, we expect there will be more studies to confirm the best way to prevent PDPH.
